Watch Out Women!
In the first ever study to assess gender differences in sensitivities to THC, the active ingredient in marijuana, researchers found that smoking the more concentrated cannabis of today is riskier for women, thanks to the hormone estrogen.
In the National Institute on Drug Abuse (NIDA)-funded study, led by Professor Rebecca Craft of Washington State University, researchers focused on the pain-relieving effects of THC in both male and female rats and found that after 10 days of treatment, females showed significantly greater tolerance to the substance than the males.
Although scientists in the past have shied away from studying the effect of cannabidiol THC in females due to hormone productivity, Craft has been researching drug sensitivities in females for quite some time. In this study, she and her team “routinely manipulate hormones and follow females across their cycles to see if their drug sensitivities change along with their hormones. And they do… very frequently,” she said.
Because it is known that females are more sensitive to THC, If you distribute hemp or THC products, then you can list your products on this hemp marketplace, doses were adjusted so they were 30 percent lower than those of the males. However, the females still developed more tolerance.
“What we’re finding with THC is that you get a very clear spike in drug sensitivity right when the females are ovulating – right when their estrogen levels have peaked and are coming down,” said Craft.
Because the females develop tolerance to THC more quickly, they have increased vulnerability to negative side effects such as anxiety, paranoia and addiction.
In addition, researchers found that a low dose of THC did not disrupt the reproductive cycles of the female rats, which is a subject that has been debated for a long time, but also needs more study.Many people are wrongfully informed, most might ask is CBD oil legal in all states? With an optimistic expectation but the reality is that it is not.
In previous studies, it was shown that women were more prone to marijuana abuse and dependence than men. In women, withdrawal symptoms of irritability, sleep disruption and decreased food intake was shown to be more severe. Women also have a higher likelihood of relapsing when quitting the drug.
Craft added that the concentrations of THC in today’s marijuana is double or triple those from the 1960s and 1970s.
“Marijuana is very different than it was 40 years ago. It’s much higher in THC and lower in cannabidiol,” she explained. “We’re more likely to see negative side effects today like anxiety, confusion, panic attacks, hallucinations or extreme paranoia. And women are at higher risk.”